Analysis Note

Colour (visual): white to yellow to beigeAppearance of substance (visual): beadsLoading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF): 0.60 - 1.00 mmol/gSwelling Volume (in CH₂Cl₂): lot specific resultThe polymer matrix is copoly (styrene-1 % DVB), 100 - 200 mesh.

General description

[3-((Methyl-Fmoc-amino)-methyl)indol-1-yl]acetyl AM resin is an extremely useful support for the production of N-methyl substituted carboxamides and sulfonamides, as well as peptide N-methylamides [1]. After first removing the Fmoc group, loading of the resin with Fmoc-amino acids can be effected using HATU/DIPEA. Cleavage with TFA directly provides the product N-methylamide.

The product number for this product was previously 01-64-0451.

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Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Linkage

Replaces: 01-64-0451